FBXL14

Across TCGA patient cohorts, FBXL14 RNA expression is significantly associated with the protein abundance of many other proteins, with 8,890 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible FBXL14-associated proteins across cancer lineages are C2CD5, WBP11, and CMAS. Each is linked with FBXL14 in more than 4 cancer types. Because this analysis shows association rather than direction, both FBXL14-to-partner and partner-to-FBXL14 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FBXL14 versus C2CD5 in BRCA, with a Pearson correlation of 0.34.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (FBXL14→partner) and Y-score (partner→FBXL14) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	C2CD5 →	+0.375	+0.749	<.001	.001	3	5
HNSC	WBP11 →	+0.260	+0.867	<.001	<.001	3	4
OV	CMAS →	+0.504	+0.726	.002	<.001	3	4
PDAC	KMT2D_S4359 →	+0.588	+0.362	.004	.003	3	4
BRCA	PTMS →	+0.515	+0.542	.001	.006	3	4
OV	WNK1 →	+0.263	+0.541	<.001	.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,890 associations by consensus.

FBXL14 vs C2CD5 — BRCA

Explore this scatter interactively →