FBXL14

Across TCGA patient cohorts, FBXL14 protein abundance is significantly associated with the RNA expression of many other genes, with 912 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible FBXL14-associated genes across cancer lineages are CEP295, GUCY2F, and NEIL3. Each is linked with FBXL14 in more than 1 cancer types. Because this analysis shows association rather than direction, both FBXL14-to-partner and partner-to-FBXL14 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FBXL14 versus CEP295 in UCEC, with a Pearson correlation of 0.61.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FBXL14→partner) and Y-score (partner→FBXL14) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	CEP295 →	+0.624	+0.848	<.001	.001	3	2
UCEC	GUCY2F →	-0.697	-0.785	.003	.003	3	1
UCEC	NEIL3 →	+1.242	+0.848	.001	.001	3	1
UCEC	TENT4A →	+0.602	+1.000	.005	.008	3	1
UCEC	TFG →	+0.387	+0.931	.001	<.001	3	1
UCEC	SLC2A1 →	+1.890	+1.044	.004	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 912 associations by consensus.

FBXL14 vs CEP295 — UCEC

Explore this scatter interactively →