FBRS

Across TCGA patient cohorts, FBRS protein abundance is significantly associated with the RNA expression of many other genes, with 1,955 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible FBRS-associated genes across cancer lineages are XPO6, CDK2, and WBP2. Each is linked with FBRS in more than 2 cancer types. Because this analysis shows association rather than direction, both FBRS-to-partner and partner-to-FBRS results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FBRS versus XPO6 in BRCA, with a Pearson correlation of 0.32.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FBRS→partner) and Y-score (partner→FBRS) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	XPO6 →	+0.448	+0.319	<.001	<.001	3	3
PDAC	CDK2 →	+0.426	+0.427	.003	.005	3	2
BRCA	WBP2 →	+0.474	+0.264	<.001	.002	3	2
PDAC	CDCA5 →	+0.629	+0.299	.002	.007	3	2
BRCA	SMG8 →	+0.551	+0.374	<.001	<.001	3	2
PDAC	GINS3 →	+0.541	+0.476	.002	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,955 associations by consensus.

FBRS vs XPO6 — BRCA

Explore this scatter interactively →