FBRS

Across TCGA cell cohorts, FBRS protein abundance is significantly associated with the go_rna of many other GO terms, with 936 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible FBRS-associated GO terms across cancer lineages are Metaphase/anaphase transition of cell cycle, Metaphase/anaphase transition of mitotic cell cycle, and Interstrand cross-link repair. Each is linked with FBRS in more than 3 cancer types. Because this analysis shows association rather than direction, both FBRS-to-partner and partner-to-FBRS results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Metaphase/anaphase transition of cell cycle grouped by FBRS-low versus FBRS-high in PANCREAS.

protein abundance associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FBRS→partner) and Y-score (partner→FBRS) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	Metaphase/anaphase transition of cell cycle →	-0.136	-1.771	<.001	.001	3	4
PANCREAS	Metaphase/anaphase transition of mitotic cell cycle →	-0.132	-1.771	<.001	.001	3	4
PANCREAS	Interstrand cross-link repair →	-0.086	-1.803	<.001	.001	3	4
PANCREAS	Transcription initiation at RNA polymerase I promoter →	-0.140	-1.613	.004	.003	3	4
BREAST	NAD-cap decapping →	+0.079	+1.424	.009	<.001	3	3
BREAST	Regulation protein catabolic process at synapse →	+0.123	+1.285	<.001	.002	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 936 associations by consensus.

Metaphase/anaphase transition of cell cycle by FBRS expression — PANCREAS

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