FBP2

Across TCGA pan-cancer cohorts, FBP2 mass-spec protein is linked to patient survival in 7 of 34 cancer types, making it a survival-associated FBP2 data layer compared with 26 for mass-spec protein and 9 for mutation status.

The strongest signal is observed in clear cell renal cell carcinoma (CCRCC), where higher FBP2 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated FBP2 expression acts as an unfavorable survival marker, although some lineages such as CCRCC and PDAC show a favorable association.

CCRCC, PDAC, and HNSC are the cancer types where FBP2 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CCRCC	DFS	Median	IV	0.861	0.131	.001	53	view →
PDAC	OS	Quartile	All	0.495	0.255	.004	41	view →
HNSC	OS	Median	All	0.933	1.000	.002	9	view →
COAD	DFS	Median	III,IV	0.846	1.000	.045	6	view →
GBM	OS	Quartile	All	0.421	0.742	.018	5	view →
LUAD	OS	Median	III,IV	0.882	0.362	.021	2	view →
LSCC	DFS	Quartile	III,IV	0.640	1.000	.049	1	view →

Pink = unfavorable, green = favorable. Showing the 7 strongest of 7 lineages.

FBP2–CCRCC (DFS)

Open the CCRCC breakdown →