FBP2

Across TCGA patient cohorts, FBP2 mutation is significantly associated with the RNA expression of many other genes, with 1,444 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FBP2-associated genes across cancer lineages are COX5BP8, RNU6-921P, and RNU7-67P. Each is linked with FBP2 in more than 1 cancer types. Because this analysis shows association rather than direction, both FBP2-to-partner and partner-to-FBP2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, COX5BP8 grouped by FBP2-low versus FBP2-high in STAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FBP2→partner) and Y-score (partner→FBP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	COX5BP8 →	+0.315	+3.953	.005	.006	3	2
LUAD	RNU6-921P →	+0.322	+4.481	<.001	.009	3	2
LUAD	RNU7-67P →	+0.829	+6.599	<.001	<.001	3	2
LUAD	MIR4779 →	+0.513	+5.285	<.001	.001	3	2
UCEC	MYCL →	-0.723	-3.574	.006	.002	3	2
UCEC	MIR4698 →	+0.248	+2.653	.004	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,444 associations by consensus.

COX5BP8 by FBP2 expression — STAD

Explore this box plot interactively →