FBP2

Across TCGA cell cohorts, FBP2 mutation is significantly associated with the RNA expression of many other genes, with 10 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible FBP2-associated genes across cancer lineages are RGSL1, RBMY1J, and ARMH2. Each is linked with FBP2 in more than 1 cancer types. Because this analysis shows association rather than direction, both FBP2-to-partner and partner-to-FBP2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RGSL1 grouped by FBP2-low versus FBP2-high in OVARY.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FBP2→partner) and Y-score (partner→FBP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	RGSL1 →	+0.065	+4.228	<.001	.006	3	1
OVARY	RBMY1J →	+0.017	+4.807	<.001	.003	3	1
OVARY	ARMH2 →	+0.031	+4.228	.007	.006	3	1
BLOOD_Leukemia	OR51T1 →	+0.071	+4.922	<.001	.009	3	1
BLOOD_Leukemia	GSG1L2 →	+0.058	+5.969	<.001	.001	3	1
BLOOD_Leukemia	OR4M2 →	+0.034	+4.922	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 10 associations by consensus.

RGSL1 by FBP2 expression — OVARY

Explore this box plot interactively →