FBLN7

mass-spec protein & survival
Survivalmass-specKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, FBLN7 mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated FBLN7 data layer compared with 24 for mass-spec protein and 3 for mutation status.

The strongest signal is observed in clear cell renal cell carcinoma (CCRCC), where higher FBLN7 mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated FBLN7 expression acts as an unfavorable survival marker.

CCRCC, LUAD, and LSCC are the cancer types where FBLN7 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
CCRCCDFSMedianIII,IV0.1050.928.00327view →
LUADOSMedianII,III,IV0.7951.000.00519view →
LSCCDFSTertileII,III,IV0.7931.000.00811view →
PDACDFSMedianAll0.7220.871.0433view →
GBMOSMedianAll0.2790.484.0302view →
Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

FBLN7–CCRCC (DFS)

Kaplan–Meier survival curve for FBLN7 mass-spec protein-high vs -low samples in CCRCC.

Open the CCRCC breakdown →

Exploration