FBLN7

Across TCGA patient cohorts, FBLN7 mutation is significantly associated with the RNA expression of many other genes, with 1,963 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FBLN7-associated genes across cancer lineages are JMJD6, DHDDS, and SEC61GP1. Each is linked with FBLN7 in more than 2 cancer types. Because this analysis shows association rather than direction, both FBLN7-to-partner and partner-to-FBLN7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, JMJD6 grouped by FBLN7-low versus FBLN7-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FBLN7→partner) and Y-score (partner→FBLN7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	JMJD6 →	+0.403	+2.736	.001	<.001	3	3
SKCM	DHDDS →	+0.410	+2.783	.008	.002	3	3
HNSC	SEC61GP1 →	+0.826	+5.063	<.001	.001	3	2
READ	MIR4774 →	+0.841	+6.257	<.001	.001	3	2
CESC	COX6CP16 →	+0.194	+5.269	<.001	.001	3	2
UCEC	COX15 →	+0.428	+3.008	.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,963 associations by consensus.

JMJD6 by FBLN7 expression — UCEC

Explore this box plot interactively →