FBLN7

Across TCGA cell cohorts, FBLN7 mutation is significantly associated with the RNA expression of many other genes, with 4 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible FBLN7-associated genes across cancer lineages are PRR23C, DIRC1, and CFHR2. Each is linked with FBLN7 in more than 1 cancer types. Because this analysis shows association rather than direction, both FBLN7-to-partner and partner-to-FBLN7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PRR23C grouped by FBLN7-low versus FBLN7-high in OVARY.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FBLN7→partner) and Y-score (partner→FBLN7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	PRR23C →	+0.012	+4.990	<.001	.001	3	1
LARGE_INTESTINE	DIRC1 →	+0.003	+4.022	<.001	.006	3	1
LARGE_INTESTINE	CFHR2 →	+0.038	+4.022	<.001	.006	3	1
LUNG_NSCLC_LUAD	KRTAP20-2 →	+0.269	+4.887	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

PRR23C by FBLN7 expression — OVARY

Explore this box plot interactively →