FBLN1

Across TCGA patient cohorts, FBLN1 mutation is significantly associated with the RNA expression of many other genes, with 1,898 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FBLN1-associated genes across cancer lineages are ZNF367, ZMYND19, and THOP1. Each is linked with FBLN1 in more than 2 cancer types. Because this analysis shows association rather than direction, both FBLN1-to-partner and partner-to-FBLN1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ZNF367 grouped by FBLN1-low versus FBLN1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FBLN1→partner) and Y-score (partner→FBLN1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ZNF367 →	+0.635	+2.436	<.001	.001	3	3
UCEC	ZMYND19 →	+0.373	+2.169	<.001	.002	3	3
UCEC	THOP1 →	+0.397	+1.522	.001	.009	3	3
UCEC	CACYBPP2 →	+0.434	+2.272	<.001	.001	3	3
UCEC	GRPEL1 →	+0.305	+1.617	.003	.005	3	3
UCEC	CEP78 →	+0.342	+1.617	.009	.009	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,898 associations by consensus.

ZNF367 by FBLN1 expression — UCEC

Explore this box plot interactively →