FBLIM1

Across TCGA pan-cancer cohorts, FBLIM1 mass-spec protein is linked to patient survival in 6 of 34 cancer types, making it a survival-associated FBLIM1 data layer compared with 22 for mass-spec protein and 2 for mutation status.

The strongest signal is observed in clear cell renal cell carcinoma (CCRCC), where higher FBLIM1 mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated FBLIM1 expression acts as an unfavorable survival marker, although some lineages such as HNSC and LUAD show a favorable association.

CCRCC, LSCC, and GBM are the cancer types where FBLIM1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CCRCC	DFS	Tertile	II,III,IV	0.140	0.972	.006	33	view →
LSCC	DFS	Tertile	II,III,IV	0.659	0.907	.011	17	view →
GBM	DFS	Quartile	All	0.241	0.544	.004	11	view →
HNSC	DFS	Median	All	0.733	0.539	.009	10	view →
PDAC	DFS	Median	IV	0.214	0.785	.006	9	view →
LUAD	OS	Quartile	All	1.000	0.917	.025	4	view →

Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

FBLIM1–CCRCC (DFS)

Open the CCRCC breakdown →