FBLIM1

Across TCGA patient cohorts, FBLIM1 mutation is significantly associated with the RNA expression of many other genes, with 535 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FBLIM1-associated genes across cancer lineages are RAD51, CHAF1A, and C16orf95. Each is linked with FBLIM1 in more than 2 cancer types. Because this analysis shows association rather than direction, both FBLIM1-to-partner and partner-to-FBLIM1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RAD51 grouped by FBLIM1-low versus FBLIM1-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FBLIM1→partner) and Y-score (partner→FBLIM1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	RAD51 →	+0.419	+1.919	.009	.008	3	3
UCEC	CHAF1A →	+0.604	+3.606	.008	.001	3	3
UCEC	C16orf95 →	+0.308	+3.584	.006	.003	3	2
SKCM	NCOR1P2 →	+0.052	+2.362	.001	.003	3	2
UCEC	GCHFR →	+0.973	+3.584	.002	.003	3	2
SKCM	OIP5 →	+0.559	+2.116	.001	.002	2	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 535 associations by consensus.

RAD51 by FBLIM1 expression — SKCM

Explore this box plot interactively →