FBLIM1

Across TCGA cell cohorts, FBLIM1 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,091 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible FBLIM1-associated GO terms across cancer lineages are Regulation of protein modification by small protein conjugation or removal, Regulation of tumor necrosis factor superfamily cytokine production, and Regulation of tumor necrosis factor production. Each is linked with FBLIM1 in more than 9 cancer types. Because this analysis shows association rather than direction, both FBLIM1-to-partner and partner-to-FBLIM1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of protein modification by small protein conjugation or removal grouped by FBLIM1-low versus FBLIM1-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FBLIM1→partner) and Y-score (partner→FBLIM1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	Regulation of protein modification by small protein conjugation or removal →	+0.048	+1.816	.008	.001	3	10
BREAST	Regulation of tumor necrosis factor superfamily cytokine production →	+0.092	+2.437	<.001	<.001	3	10
BREAST	Regulation of tumor necrosis factor production →	+0.096	+2.437	<.001	<.001	3	10
UPPER_AERODIGESTIVE_TRACT	Protein localization to plasma membrane →	+0.060	+1.241	.001	<.001	3	10
UPPER_AERODIGESTIVE_TRACT	Regulation of Rho protein signal transduction →	+0.093	+1.203	<.001	<.001	3	10
SKIN	ERBB signaling pathway →	+0.074	+2.546	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,091 associations by consensus.

Regulation of protein modification by small protein conjugation or removal by FBLIM1 expression — OVARY

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