FBLIM1

Across TCGA cell cohorts, FBLIM1 mutation is significantly associated with the RNA expression of many other genes, with 75 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible FBLIM1-associated genes across cancer lineages are NEUROD4, SCT, and CACNG2. Each is linked with FBLIM1 in more than 1 cancer types. Because this analysis shows association rather than direction, both FBLIM1-to-partner and partner-to-FBLIM1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, NEUROD4 grouped by FBLIM1-low versus FBLIM1-high in OESOPHAGUS.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FBLIM1→partner) and Y-score (partner→FBLIM1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	NEUROD4 →	+0.049	+4.017	.002	.007	3	2
OESOPHAGUS	SCT →	+0.241	+4.017	<.001	.007	3	1
BLOOD_Leukemia	CACNG2 →	+0.016	+5.539	<.001	.003	3	1
SKIN	AMELX →	+0.038	+4.977	<.001	.007	3	1
LARGE_INTESTINE	TNFRSF10A →	+0.857	+3.064	.005	.009	3	1
LARGE_INTESTINE	SERAC1 →	+0.734	+3.212	.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 75 associations by consensus.

NEUROD4 by FBLIM1 expression — OESOPHAGUS

Explore this box plot interactively →