FBL

Across TCGA patient cohorts, FBL protein abundance is significantly associated with the RNA expression of many other genes, with 17,061 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible FBL-associated genes across cancer lineages are ZFAS1, SIGLEC9, and CD300C. Each is linked with FBL in more than 7 cancer types. Because this analysis shows association rather than direction, both FBL-to-partner and partner-to-FBL results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FBL versus ZFAS1 in CCRCC, with a Pearson correlation of 0.40.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FBL→partner) and Y-score (partner→FBL) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	ZFAS1 →	+0.611	+0.244	<.001	<.001	3	8
GBM	SIGLEC9 →	-0.805	-0.311	.001	<.001	3	7
OV	CD300C →	-0.810	-0.528	<.001	.003	3	7
OV	RPS21 →	+0.819	+0.438	<.001	<.001	3	7
OV	GAS5 →	+0.922	+0.499	<.001	<.001	3	7
BRCA	RPS16 →	+0.788	+0.347	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,061 associations by consensus.

FBL vs ZFAS1 — CCRCC

Explore this scatter interactively →