Across TCGA cell cohorts, FBF1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,697 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible FBF1-associated GO terms across cancer lineages are Microtubule nucleation, Negative regulation of RNA splicing, and Positive regulation of intracellular steroid hormone receptor signaling pathway. Each is linked with FBF1 in more than 16 cancer types. Because this analysis shows association rather than direction, both FBF1-to-partner and partner-to-FBF1 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FBF1→partner) and Y-score (partner→FBF1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	Microtubule nucleation →	+0.137	+1.431	<.001	<.001	3	17
UPPER_AERODIGESTIVE_TRACT	Negative regulation of RNA splicing →	+0.126	+1.665	<.001	<.001	3	16
BREAST	Positive regulation of intracellular steroid hormone receptor signaling pathway →	+0.136	+1.144	<.001	<.001	3	16
PANCREAS	Negative regulation of centrosome duplication →	+0.112	+1.072	<.001	<.001	3	16
UPPER_AERODIGESTIVE_TRACT	Negative regulation of calcium ion export across plasma membrane →	+0.079	+1.090	<.001	<.001	3	16
PANCREAS	Negative regulation of centrosome cycle →	+0.112	+1.072	<.001	<.001	3	16

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,697 associations by consensus.

Exploration

FBF1 survival (RNA) · tumor vs normal (RNA) · all FBF1 data types