Across TCGA cell cohorts, FBF1 mutation is significantly associated with the RNA expression of many other genes, with 201 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible FBF1-associated genes across cancer lineages are GPR101, ZP1, and CD1E. Each is linked with FBF1 in more than 1 cancer types. Because this analysis shows association rather than direction, both FBF1-to-partner and partner-to-FBF1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FBF1→partner) and Y-score (partner→FBF1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	GPR101 →	+0.020	+5.087	<.001	.004	3	2
BLOOD_Leukemia	ZP1 →	+1.073	+3.376	<.001	.006	3	2
BLOOD_Leukemia	CD1E →	+3.602	+3.553	<.001	.004	3	2
LARGE_INTESTINE	PRKAA2 →	+1.035	+3.404	<.001	.001	3	2
LARGE_INTESTINE	GLOD4 →	+0.576	+2.451	.003	.009	3	2
CNS	GZMH →	+0.024	+4.772	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 201 associations by consensus.

Exploration

FBF1 survival (RNA) · tumor vs normal (RNA) · all FBF1 data types