FAXDC2

Across TCGA cell cohorts, FAXDC2 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,787 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible FAXDC2-associated GO terms across cancer lineages are Process utilizing autophagic mechanism, Autophagy, and Macroautophagy. Each is linked with FAXDC2 in more than 10 cancer types. Because this analysis shows association rather than direction, both FAXDC2-to-partner and partner-to-FAXDC2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Process utilizing autophagic mechanism grouped by FAXDC2-low versus FAXDC2-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FAXDC2→partner) and Y-score (partner→FAXDC2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Process utilizing autophagic mechanism →	+0.080	+1.277	<.001	.001	3	11
UPPER_AERODIGESTIVE_TRACT	Autophagy →	+0.080	+1.277	<.001	.001	3	11
UPPER_AERODIGESTIVE_TRACT	Macroautophagy →	+0.080	+1.299	<.001	<.001	3	10
UPPER_AERODIGESTIVE_TRACT	Regulation of macroautophagy →	+0.081	+1.288	<.001	.001	3	10
OESOPHAGUS	Negative regulation of myoblast fusion →	+0.192	+1.391	<.001	.009	3	10
UPPER_AERODIGESTIVE_TRACT	Golgi vesicle transport →	+0.072	+1.153	.001	.002	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,787 associations by consensus.

Process utilizing autophagic mechanism by FAXDC2 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →