FAXDC2

Across TCGA cell cohorts, FAXDC2 mutation is significantly associated with the RNA expression of many other genes, with 5 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible FAXDC2-associated genes across cancer lineages are MYF6, OR1L6, and OR10K1. Each is linked with FAXDC2 in more than 1 cancer types. Because this analysis shows association rather than direction, both FAXDC2-to-partner and partner-to-FAXDC2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MYF6 grouped by FAXDC2-low versus FAXDC2-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAXDC2→partner) and Y-score (partner→FAXDC2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	MYF6 →	+0.014	+4.415	<.001	.007	3	1
LARGE_INTESTINE	OR1L6 →	+0.027	+5.022	<.001	.002	3	1
LARGE_INTESTINE	OR10K1 →	+0.005	+5.022	<.001	.002	3	1
LARGE_INTESTINE	MAGEB3 →	+0.047	+4.467	.002	.004	3	1
LARGE_INTESTINE	INSRR →	+0.047	+4.584	<.001	.003	1	1

Each partner links to its Q-omics profile. Showing the 5 strongest of 5 associations by consensus.

MYF6 by FAXDC2 expression — LARGE_INTESTINE

Explore this box plot interactively →