FAXC

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, FAXC RNA expression is significantly associated with the protein abundance of many other proteins, with 20,744 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible FAXC-associated proteins across cancer lineages are PFN2, PHIP, and UCHL1. Each is linked with FAXC in more than 5 cancer types. Because this analysis shows association rather than direction, both FAXC-to-partner and partner-to-FAXC results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FAXC versus PFN2 in LSCC, with a Pearson correlation of 0.43.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (FAXC→partner) and Y-score (partner→FAXC) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LSCCPFN2 →+0.660+1.095<.001<.00136
HNSCPHIP →+0.380+1.061<.001<.00135
CCRCCUCHL1 →+1.267+0.493<.001<.00135
BRCAFCHO2 →-0.251-0.520<.001.00135
LSCCDEF6 →-0.302-0.894<.001<.00134
LSCCPXN_S322 →-0.460-0.967<.001<.00134
Each partner links to its Q-omics profile. Showing the 6 strongest of 20,744 associations by consensus.

FAXC vs PFN2 — LSCC

Per-sample scatter of FAXC vs PFN2 in LSCC (Pearson r = 0.43).

Explore this scatter interactively →

Exploration