FAXC

Across TCGA cell cohorts, FAXC mutation is significantly associated with the RNA expression of many other genes, with 13 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible FAXC-associated genes across cancer lineages are BTBD16, OR9G1, and LRRC72. Each is linked with FAXC in more than 1 cancer types. Because this analysis shows association rather than direction, both FAXC-to-partner and partner-to-FAXC results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, BTBD16 grouped by FAXC-low versus FAXC-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAXC→partner) and Y-score (partner→FAXC) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	BTBD16 →	+0.070	+3.959	<.001	.005	3	1
BLOOD_Leukemia	OR9G1 →	+0.229	+4.289	<.001	<.001	3	1
BLOOD_Leukemia	LRRC72 →	+0.024	+3.289	<.001	.009	3	1
BLOOD_Leukemia	OR5M1 →	+0.010	+4.569	<.001	.003	3	1
BLOOD_Leukemia	TRPM3 →	+0.053	+3.710	<.001	.002	3	1
LARGE_INTESTINE	UBE2QL1 →	+0.308	+3.722	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 13 associations by consensus.

BTBD16 by FAXC expression — BLOOD_Leukemia

Explore this box plot interactively →