FAUP1

Across TCGA pan-cancer cohorts, FAUP1 RNA differs between tumor and matched normal tissue in 9 of 18 cancer types tested, making tumor–normal expression one of FAUP1’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where FAUP1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types FAUP1 is over-expressed in tumor, although a few such as BRCA and STAD show the opposite, repressed pattern.

KIRC, COAD, and LIHC are the cancer types where FAUP1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in FAUP1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	Female	All	+0.651	<.001	9	view →
COAD	Female	II,III,IV	+2.422	<.001	6	view →
LIHC	All	II,III,IV	+0.468	<.001	5	view →
BRCA	Female	All	−0.194	.014	4	view →
THCA	Female	II,III,IV	+0.627	.006	2	view →
HNSC	All	All	+0.238	.040	2	view →
CHOL	All	All	+0.553	.023	1	view →
STAD	Male	IV	−0.480	.040	1	view →
KICH	Female	All	−0.293	.032	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 9 strongest of 9 lineages.

FAUP1–KIRC

Open the KIRC breakdown →