FAU

Across TCGA pan-cancer cohorts, FAU mass-spec protein is linked to patient survival in 4 of 34 cancer types, making it a survival-associated FAU data layer compared with 26 for mass-spec protein and 3 for mutation status.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher FAU mass-spec protein is associated with better overall survival. In most high-consensus cancer types, elevated FAU expression acts as an unfavorable survival marker, although some lineages such as LUAD and PDAC show a favorable association.

LUAD, CCRCC, and PDAC are the cancer types where FAU mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	OS	Tertile	All	0.868	0.524	.013	10	view →
CCRCC	DFS	Median	All	0.646	0.851	.028	7	view →
PDAC	OS	Quartile	III,IV	1.000	0.220	.024	7	view →
HNSC	OS	Median	III,IV	1.000	0.948	.043	1	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

FAU–LUAD (OS)

Open the LUAD breakdown →