FAU

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, FAU protein abundance is significantly associated with the RNA expression of many other genes, with 5,855 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible FAU-associated genes across cancer lineages are FCGR3B, CXCR1, and CXCL8. Each is linked with FAU in more than 4 cancer types. Because this analysis shows association rather than direction, both FAU-to-partner and partner-to-FAU results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FAU versus FCGR3B in OV, with a Pearson correlation of -0.51.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAU→partner) and Y-score (partner→FAU) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
OVFCGR3B →-1.489-0.705<.001<.00134
HNSCCXCR1 →-1.256-0.726<.001<.00134
GBMCXCL8 →-1.779-0.874.003<.00125
GBMFPR2 →-1.110-0.788.001.00134
HNSCADGRG3 →-0.966-0.555<.001.00534
HNSCAQP9 →-1.394-0.737<.001<.00133
Each partner links to its Q-omics profile. Showing the 6 strongest of 5,855 associations by consensus.

FAU vs FCGR3B — OV

Per-sample scatter of FAU vs FCGR3B in OV (Pearson r = -0.51).

Explore this scatter interactively →

Exploration