FAU

Across TCGA patient cohorts, FAU mutation is significantly associated with the total protein of many other genes, with 12 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FAU-associated genes across cancer lineages are PDCD4, Stathmin, and Tuberin. Each is linked with FAU in more than 1 cancer types. Because this analysis shows association rather than direction, both FAU-to-partner and partner-to-FAU results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PDCD4 grouped by FAU-low versus FAU-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAU→partner) and Y-score (partner→FAU) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	PDCD4 →	-0.689	-3.000	.011	.037	3	1
UCEC	Stathmin →	+0.164	+3.000	.039	.037	3	1
UCEC	Tuberin →	+0.359	+2.817	.021	.036	3	1
UCEC	PCNA →	+0.272	+3.000	.029	.037	2	1
UCEC	Caspase-8 →	-0.377	-3.000	.009	.036	2	1
UCEC	Acetyl-a-Tubulin-Lys40 →	+0.604	+3.000	.040	.037	1	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 12 associations by consensus.

PDCD4 by FAU expression — UCEC

Explore this box plot interactively →