FATE1

Across TCGA cell cohorts, FATE1 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,663 significant associations in total. BONE shows the largest number of these associations.

The most reproducible FATE1-associated GO terms across cancer lineages are CD8-positive, alpha-beta T cell differentiation, CD8-positive, alpha-beta T cell homeostasis, and CD8-positive, alpha-beta T cell activation. Each is linked with FATE1 in more than 5 cancer types. Because this analysis shows association rather than direction, both FATE1-to-partner and partner-to-FATE1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CD8-positive, alpha-beta T cell differentiation grouped by FATE1-low versus FATE1-high in LARGE_INTESTINE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FATE1→partner) and Y-score (partner→FATE1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	CD8-positive, alpha-beta T cell differentiation →	+0.113	+0.019	<.001	.006	3	6
BONE	CD8-positive, alpha-beta T cell homeostasis →	+0.087	+0.379	<.001	.004	3	5
LARGE_INTESTINE	CD8-positive, alpha-beta T cell activation →	+0.122	+0.019	<.001	.006	3	4
BONE	Thymic T cell selection →	+0.078	+0.551	.006	.007	2	5
BONE	T-helper 17 type immune response →	+0.141	+0.471	<.001	<.001	3	4
BONE	T-helper 17 cell differentiation →	+0.128	+0.471	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,663 associations by consensus.

CD8-positive, alpha-beta T cell differentiation by FATE1 expression — LARGE_INTESTINE

Explore this box plot interactively →