Across TCGA pan-cancer cohorts, FASTKD5 mass-spec protein is linked to patient survival in 3 of 34 cancer types, making it a survival-associated FASTKD5 data layer compared with 25 for mass-spec protein and 4 for mutation status.

The strongest signal is observed in pancreatic ductal adenocarcinoma (PDAC), where higher FASTKD5 mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated FASTKD5 expression acts as an unfavorable survival marker.

PDAC, HNSC, and LUAD are the cancer types where FASTKD5 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
PDAC	DFS	Median	III,IV	0.513	0.872	.015	4	view →
HNSC	OS	Tertile	All	0.806	0.906	.034	2	view →
LUAD	DFS	Tertile	II,III,IV	0.315	0.849	.014	2	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

Exploration

Same gene, other analysis: FASTKD5 tumor-vs-normal RNA expression · all FASTKD5 data types