FASTKD2

Across TCGA patient cohorts, FASTKD2 protein abundance is significantly associated with the RNA expression of many other genes, with 17,222 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible FASTKD2-associated genes across cancer lineages are ARHGEF6, PDE1A, and COX7A1. Each is linked with FASTKD2 in more than 6 cancer types. Because this analysis shows association rather than direction, both FASTKD2-to-partner and partner-to-FASTKD2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FASTKD2 versus ARHGEF6 in BRCA, with a Pearson correlation of -0.38.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FASTKD2→partner) and Y-score (partner→FASTKD2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	ARHGEF6 →	-0.981	-0.403	<.001	<.001	3	7
BRCA	PDE1A →	-0.823	-0.425	<.001	<.001	3	6
BRCA	COX7A1 →	-0.938	-0.281	<.001	<.001	3	6
BRCA	ZNF25 →	-0.586	-0.376	<.001	<.001	3	6
COAD	LINC01094 →	-0.682	-0.275	<.001	.001	3	6
BRCA	MEF2C →	-0.749	-0.412	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,222 associations by consensus.

FASTKD2 vs ARHGEF6 — BRCA

Explore this scatter interactively →