FASTKD1

Across TCGA cell cohorts, FASTKD1 mutation is significantly associated with the RNA expression of many other genes, with 17 significant associations in total. URINARY_TRACT shows the largest number of these associations.

The most reproducible FASTKD1-associated genes across cancer lineages are OR10H5, PTH, and TRIM49. Each is linked with FASTKD1 in more than 1 cancer types. Because this analysis shows association rather than direction, both FASTKD1-to-partner and partner-to-FASTKD1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR10H5 grouped by FASTKD1-low versus FASTKD1-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FASTKD1→partner) and Y-score (partner→FASTKD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	OR10H5 →	+0.080	+4.922	<.001	.009	3	2
URINARY_TRACT	PTH →	+0.073	+5.087	<.001	.004	3	1
URINARY_TRACT	TRIM49 →	+0.013	+5.087	<.001	.004	3	1
URINARY_TRACT	TDRD15 →	+0.013	+5.087	<.001	.004	3	1
URINARY_TRACT	OR4A47 →	+0.026	+5.087	<.001	.004	3	1
URINARY_TRACT	PRSS58 →	+0.136	+5.087	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 17 associations by consensus.

OR10H5 by FASTKD1 expression — BLOOD_Leukemia

Explore this box plot interactively →