FASN

Across TCGA patient cohorts, FASN protein abundance is significantly associated with the RNA expression of many other genes, with 9,610 significant associations in total. COAD shows the largest number of these associations.

The most reproducible FASN-associated genes across cancer lineages are KPNA2, PYCR1, and ALYREF. Each is linked with FASN in more than 6 cancer types. Because this analysis shows association rather than direction, both FASN-to-partner and partner-to-FASN results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FASN versus KPNA2 in OV, with a Pearson correlation of 0.36.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FASN→partner) and Y-score (partner→FASN) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	KPNA2 →	+0.781	+0.362	<.001	.009	3	7
UCEC	PYCR1 →	+1.099	+0.467	.008	.003	3	7
UCEC	ALYREF →	+0.879	+0.365	.005	.003	3	7
OV	NME1 →	+0.687	+0.445	<.001	.001	3	7
OV	BIRC5 →	+1.175	+0.567	<.001	<.001	3	7
OV	SCD →	+1.143	+0.536	<.001	.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,610 associations by consensus.

FASN vs KPNA2 — OV

Explore this scatter interactively →