FARSB

mass-spec protein & survival
Survivalmass-specKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, FARSB mass-spec protein is linked to patient survival in 6 of 34 cancer types, making it a survival-associated FARSB data layer compared with 24 for mass-spec protein and 7 for mutation status.

The strongest signal is observed in colon adenocarcinoma (COAD), where higher FARSB mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated FARSB expression acts as an unfavorable survival marker, although some lineages such as COAD and PDAC show a favorable association.

COAD, PDAC, and LSCC are the cancer types where FARSB mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
COADDFSMedianAll1.0000.918.01278view →
PDACDFSTertileII,III,IV0.5080.174.01413view →
LSCCDFSTertileII,III,IV1.0000.355.0065view →
UCECDFSMedianAll0.9430.780.0094view →
HNSCDFSTertileIII,IV0.8980.706.0202view →
GBMOSQuartileAll1.0000.853.0201view →
Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

FARSB–COAD (DFS)

Kaplan–Meier survival curve for FARSB mass-spec protein-high vs -low samples in COAD.

Open the COAD breakdown →

Exploration