FARSB

Across TCGA patient cohorts, FARSB mutation is significantly associated with the RNA expression of many other genes, with 1,775 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FARSB-associated genes across cancer lineages are ARPP19P2, C1QBPP1, and CDC42P2. Each is linked with FARSB in more than 2 cancer types. Because this analysis shows association rather than direction, both FARSB-to-partner and partner-to-FARSB results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ARPP19P2 grouped by FARSB-low versus FARSB-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FARSB→partner) and Y-score (partner→FARSB) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ARPP19P2 →	+0.154	+1.588	.003	.006	3	3
BLCA	C1QBPP1 →	+0.127	+6.018	<.001	.002	3	2
SKCM	CDC42P2 →	+0.239	+3.801	<.001	.005	3	2
HNSC	RNU6-796P →	+0.179	+4.221	<.001	.008	3	2
SKCM	UGT1A6 →	+0.219	+3.805	<.001	.009	3	2
SKCM	SMARCE1P2 →	+0.136	+3.701	.002	.007	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,775 associations by consensus.

ARPP19P2 by FARSB expression — UCEC

Explore this box plot interactively →