FARSB

Across TCGA cell cohorts, FARSB RNA expression is significantly associated with the go_rna of many other GO terms, with 4,091 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible FARSB-associated GO terms across cancer lineages are DNA replication initiation, Negative regulation of spindle checkpoint, and Maturation of SSU-rRNA. Each is linked with FARSB in more than 17 cancer types. Because this analysis shows association rather than direction, both FARSB-to-partner and partner-to-FARSB results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DNA replication initiation grouped by FARSB-low versus FARSB-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FARSB→partner) and Y-score (partner→FARSB) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	DNA replication initiation →	+0.164	+0.753	.001	<.001	3	18
OESOPHAGUS	Negative regulation of spindle checkpoint →	+0.261	+1.228	<.001	.001	3	16
UPPER_AERODIGESTIVE_TRACT	Maturation of SSU-rRNA →	+0.131	+1.122	<.001	<.001	3	16
UPPER_AERODIGESTIVE_TRACT	Protein localization to kinetochore →	+0.177	+1.089	<.001	<.001	3	16
OESOPHAGUS	Negative regulation of mitotic spindle assembly checkpoint signaling →	+0.261	+1.228	<.001	.001	3	16
PANCREAS	Spindle elongation →	+0.240	+0.802	<.001	<.001	3	16

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,091 associations by consensus.

DNA replication initiation by FARSB expression — BONE

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