FARSB

Across TCGA cell cohorts, FARSB mutation is significantly associated with the RNA expression of many other genes, with 14 significant associations in total. LUNG_SCLC shows the largest number of these associations.

The most reproducible FARSB-associated genes across cancer lineages are TXNDC8, KRTAP10-2, and C16orf96. Each is linked with FARSB in more than 1 cancer types. Because this analysis shows association rather than direction, both FARSB-to-partner and partner-to-FARSB results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TXNDC8 grouped by FARSB-low versus FARSB-high in KIDNEY.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FARSB→partner) and Y-score (partner→FARSB) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
KIDNEY	TXNDC8 →	+0.013	+5.000	<.001	.005	3	1
LARGE_INTESTINE	KRTAP10-2 →	+0.050	+2.994	<.001	.006	3	1
LARGE_INTESTINE	C16orf96 →	+0.519	+3.520	.003	.005	3	1
UPPER_AERODIGESTIVE_TRACT	C4orf50 →	+0.013	+4.736	<.001	.009	3	1
UPPER_AERODIGESTIVE_TRACT	TRIM77 →	+0.030	+5.357	<.001	.003	3	1
UPPER_AERODIGESTIVE_TRACT	CT45A6 →	+0.060	+5.357	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 14 associations by consensus.

TXNDC8 by FARSB expression — KIDNEY

Explore this box plot interactively →