FARSA-AS1

Across TCGA pan-cancer cohorts, FARSA-AS1 RNA is linked to patient survival in 19 of 34 cancer types, making it the most broadly survival-associated FARSA-AS1 data layer.

The strongest signal is observed in thyroid carcinoma (THCA), where higher FARSA-AS1 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated FARSA-AS1 expression acts as an unfavorable survival marker, although some lineages such as HNSC and STAD show a favorable association.

THCA, UCEC, and HNSC are the cancer types where FARSA-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
THCA	DFS	Median	II,III,IV	0.778	0.949	<.001	95	view →
UCEC	DFS	Tertile	All	0.858	0.933	<.001	92	view →
HNSC	OS	Tertile	II,III,IV	0.781	0.623	.002	47	view →
KIRC	DFS	Tertile	All	0.517	0.699	.004	29	view →
OV	DFS	Median	IV	0.337	0.577	.003	26	view →
MESO	OS	Quartile	II,III,IV	0.166	0.659	.010	21	view →
LUSC	DFS	Quartile	III,IV	0.104	0.851	<.001	14	view →
PRAD	DFS	Tertile	All	0.852	0.923	.021	12	view →
STAD	OS	Median	III,IV	0.693	0.561	.022	8	view →
THYM	DFS	Quartile	II,III,IV	1.000	0.388	.005	8	view →
ESCA	DFS	Median	II,III,IV	0.425	0.618	.004	8	view →
KIRP	OS	Median	II,III,IV	0.511	0.876	.023	8	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 19 lineages.

FARSA-AS1–THCA (DFS)

Open the THCA breakdown →