FARS2

Across TCGA patient cohorts, FARS2 mutation is significantly associated with the RNA expression of many other genes, with 415 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FARS2-associated genes across cancer lineages are LINC02647, RPL23AP82, and TRAJ56. Each is linked with FARS2 in more than 2 cancer types. Because this analysis shows association rather than direction, both FARS2-to-partner and partner-to-FARS2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LINC02647 grouped by FARS2-low versus FARS2-high in BLCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FARS2→partner) and Y-score (partner→FARS2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLCA	LINC02647 →	+0.294	+7.640	<.001	.009	3	3
UCEC	RPL23AP82 →	+0.461	+3.329	.003	.005	3	2
UCEC	TRAJ56 →	+0.390	+2.719	<.001	.006	3	2
UCEC	RNA5SP419 →	+0.734	+2.854	<.001	.001	3	2
UCEC	RNA5SP410 →	+0.683	+2.566	<.001	.002	3	2
UCEC	RNU6-479P →	+0.456	+2.566	.003	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 415 associations by consensus.

LINC02647 by FARS2 expression — BLCA

Explore this box plot interactively →