FARS2

Across TCGA cell cohorts, FARS2 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,339 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible FARS2-associated GO terms across cancer lineages are Phenylalanyl-tRNA aminoacylation, Protein peptidyl-prolyl isomerization, and Regulation of peptidyl-lysine crotonylation. Each is linked with FARS2 in more than 16 cancer types. Because this analysis shows association rather than direction, both FARS2-to-partner and partner-to-FARS2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Phenylalanyl-tRNA aminoacylation grouped by FARS2-low versus FARS2-high in BLOOD_Lymphoma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FARS2→partner) and Y-score (partner→FARS2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	Phenylalanyl-tRNA aminoacylation →	+0.131	+1.091	<.001	<.001	3	17
PANCREAS	Protein peptidyl-prolyl isomerization →	+0.120	+0.948	.003	<.001	3	12
LUNG_NSCLC_LUAD	Regulation of peptidyl-lysine crotonylation →	+0.127	+0.520	<.001	<.001	3	11
LUNG_NSCLC_LUAD	Negative regulation of peptidyl-lysine crotonylation →	+0.127	+0.520	<.001	<.001	3	11
UPPER_AERODIGESTIVE_TRACT	Negative regulation of RNA export from nucleus →	+0.129	+0.685	<.001	.001	3	9
LUNG_NSCLC_LUSC	[4Fe-4S] cluster assembly →	+0.168	+0.842	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,339 associations by consensus.

Phenylalanyl-tRNA aminoacylation by FARS2 expression — BLOOD_Lymphoma

Explore this box plot interactively →