FARP1

Across TCGA patient cohorts, FARP1 mutation is significantly associated with the total protein of many other genes, with 48 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FARP1-associated genes across cancer lineages are Caspase-7-cleavedD198, PCNA, and PKC-delta_pS664. Each is linked with FARP1 in more than 4 cancer types. Because this analysis shows association rather than direction, both FARP1-to-partner and partner-to-FARP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Caspase-7-cleavedD198 grouped by FARP1-low versus FARP1-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FARP1→partner) and Y-score (partner→FARP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	Caspase-7-cleavedD198 →	+1.355	+3.178	<.001	.010	3	5
COAD	PCNA →	+0.283	+3.178	.020	.010	2	4
UCEC	PKC-delta_pS664 →	-0.070	-1.415	.048	.040	3	3
UCEC	ATM →	-0.535	-2.156	<.001	.002	3	3
SKCM	FOXO3a_pS318_S321 →	+0.257	+2.824	<.001	.034	3	2
COAD	eEF2 →	+0.402	+3.178	.005	.010	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 48 associations by consensus.

Caspase-7-cleavedD198 by FARP1 expression — COAD

Explore this box plot interactively →