FARP1

Across TCGA cell cohorts, FARP1 mutation is significantly associated with the RNA expression of many other genes, with 443 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible FARP1-associated genes across cancer lineages are PRSS58, KRT71, and DMRTC2. Each is linked with FARP1 in more than 1 cancer types. Because this analysis shows association rather than direction, both FARP1-to-partner and partner-to-FARP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PRSS58 grouped by FARP1-low versus FARP1-high in PANCREAS.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FARP1→partner) and Y-score (partner→FARP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	PRSS58 →	+0.092	+5.000	<.001	.006	3	1
SOFT_TISSUE	KRT71 →	+0.006	+5.369	<.001	.004	3	1
SOFT_TISSUE	DMRTC2 →	+0.026	+5.369	<.001	.004	3	1
SOFT_TISSUE	PRY2 →	+0.026	+5.977	<.001	.001	3	1
SOFT_TISSUE	DTHD1 →	+0.006	+4.930	<.001	.008	3	1
SOFT_TISSUE	SLC22A6 →	+0.025	+4.930	<.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 443 associations by consensus.

PRSS58 by FARP1 expression — PANCREAS

Explore this box plot interactively →