FARP1

Across TCGA cell cohorts, FARP1 mutation is significantly associated with the mutation status of many other genes, with 6,808 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible FARP1-associated genes across cancer lineages are GREB1, BNC2, and MUC19. Each is linked with FARP1 in more than 5 cancer types. Because this analysis shows association rather than direction, both FARP1-to-partner and partner-to-FARP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GREB1 grouped by FARP1-low versus FARP1-high in CNS.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FARP1→partner) and Y-score (partner→FARP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CNS	GREB1 →	+2.862	+3.633	.008	.008	1	6
PANCREAS	BNC2 →	+5.115	+5.115	.005	.005	1	5
PANCREAS	MUC19 →	+5.115	+5.115	.005	.005	1	5
SKIN	TYK2 →	+3.169	+4.548	.004	.004	1	5
LUNG_NSCLC_LUAD	SIPA1L3 →	+5.772	+5.772	.002	.002	1	5
STOMACH	PDZD8 →	+4.584	+3.942	.002	.002	1	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,808 associations by consensus.

GREB1 by FARP1 expression — CNS

Explore this box plot interactively →