FAR2

Across TCGA patient cohorts, FAR2 mutation is significantly associated with the RNA expression of many other genes, with 1,960 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FAR2-associated genes across cancer lineages are TMEM97P2, MCAT, and DHRS2. Each is linked with FAR2 in more than 1 cancer types. Because this analysis shows association rather than direction, both FAR2-to-partner and partner-to-FAR2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TMEM97P2 grouped by FAR2-low versus FAR2-high in BRCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAR2→partner) and Y-score (partner→FAR2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	TMEM97P2 →	+0.117	+5.378	<.001	.006	3	2
UCEC	MCAT →	+0.370	+3.502	.003	.002	3	2
UCEC	DHRS2 →	+1.018	+2.486	<.001	.001	3	2
UCEC	NDUFAF5 →	+0.388	+3.534	<.001	<.001	3	2
UCEC	AAGAB →	+0.422	+1.968	.002	.002	3	2
UCEC	RAB11A →	+0.371	+2.914	.005	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,960 associations by consensus.

TMEM97P2 by FAR2 expression — BRCA

Explore this box plot interactively →