FAR2

Across TCGA cell cohorts, FAR2 mutation is significantly associated with the RNA expression of many other genes, with 9 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible FAR2-associated genes across cancer lineages are OR4K1, OR52A5, and GSTA5. Each is linked with FAR2 in more than 1 cancer types. Because this analysis shows association rather than direction, both FAR2-to-partner and partner-to-FAR2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR4K1 grouped by FAR2-low versus FAR2-high in SOFT_TISSUE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAR2→partner) and Y-score (partner→FAR2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	OR4K1 →	+0.020	+5.977	<.001	.001	3	1
SOFT_TISSUE	OR52A5 →	+0.013	+5.369	<.001	.004	3	1
SOFT_TISSUE	GSTA5 →	+0.021	+4.930	.001	.008	3	1
SOFT_TISSUE	OR56A4 →	+0.016	+5.977	<.001	.001	3	1
LARGE_INTESTINE	OR10W1 →	+0.022	+4.977	<.001	.007	3	1
BLOOD_Leukemia	TEX48 →	+0.047	+5.060	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 9 associations by consensus.

OR4K1 by FAR2 expression — SOFT_TISSUE

Explore this box plot interactively →