Across TCGA pan-cancer cohorts, FAR1 Mutation is linked to patient survival in 5 of 34 cancer types, making it a survival-associated FAR1 data layer compared with 21 for mass-spec protein and 3 for mass-spec protein.

The strongest signal is observed in breast invasive carcinoma (BRCA), where higher FAR1 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated FAR1 expression acts as an unfavorable survival marker, although some lineages such as UCEC show a favorable association.

BRCA, BLCA, and LIHC are the cancer types where FAR1 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
BRCA	OS	Median	All	0.124	0.924	<.001	48	view →
BLCA	DFS	Median	All	0.094	0.594	.001	21	view →
LIHC	OS	Median	All	0.185	0.778	<.001	15	view →
UCEC	DFS	Median	All	0.962	0.626	.016	12	view →
HNSC	OS	Median	All	0.390	0.687	.023	3	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

Exploration

Same gene, other analysis: FAR1 tumor-vs-normal RNA expression · all FAR1 data types