FAR1

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, FAR1 mutation is significantly associated with the RNA expression of many other genes, with 5,093 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FAR1-associated genes across cancer lineages are RNA5SP408, RNA5SP418, and RPL31P45. Each is linked with FAR1 in more than 2 cancer types. Because this analysis shows association rather than direction, both FAR1-to-partner and partner-to-FAR1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAR1→partner) and Y-score (partner→FAR1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LUADRNA5SP408 →+0.308+7.930<.001.00833
UCECRNA5SP418 →+0.630+1.937<.001.00133
SKCMRPL31P45 →+0.073+3.533.006.00133
HNSCOR1E3 →+0.049+4.767<.001.00132
HNSCMIR670 →+0.301+6.038<.001<.00132
BLCARN7SL560P →+0.300+4.840<.001.00232
Each partner links to its Q-omics profile. Showing the 6 strongest of 5,093 associations by consensus.

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