Across TCGA cell cohorts, FANCM RNA expression is significantly associated with the go_rna of many other GO terms, with 4,176 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible FANCM-associated GO terms across cancer lineages are Protein localization to condensed chromosome, Double-strand break repair via synthesis-dependent strand annealing, and Regulation of centrosome duplication. Each is linked with FANCM in more than 19 cancer types. Because this analysis shows association rather than direction, both FANCM-to-partner and partner-to-FANCM results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FANCM→partner) and Y-score (partner→FANCM) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Protein localization to condensed chromosome →	+0.184	+1.178	<.001	.001	3	20
OESOPHAGUS	Double-strand break repair via synthesis-dependent strand annealing →	+0.101	+1.143	<.001	<.001	3	20
LUNG_SCLC	Regulation of centrosome duplication →	+0.084	+0.530	.001	.004	3	19
OESOPHAGUS	Meiotic cell cycle process →	+0.090	+1.240	<.001	<.001	3	19
OESOPHAGUS	Nuclear division →	+0.085	+0.990	<.001	<.001	3	19
LUNG_SCLC	Replication fork processing →	+0.110	+0.747	<.001	<.001	3	19

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,176 associations by consensus.

Exploration

FANCM survival (RNA) · tumor vs normal (RNA) · all FANCM data types