FANCI

Across TCGA cell cohorts, FANCI RNA expression is significantly associated with the RNA expression of many other genes, with 11,129 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible FANCI-associated genes across cancer lineages are NCAPG2, FEN1, and ATAD5. Each is linked with FANCI in more than 19 cancer types. Because this analysis shows association rather than direction, both FANCI-to-partner and partner-to-FANCI results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FANCI versus NCAPG2 in BLOOD_Myeloma, with a Pearson correlation of 0.76.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FANCI→partner) and Y-score (partner→FANCI) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Myeloma	NCAPG2 →	+1.496	+1.486	<.001	<.001	3	19
BONE	FEN1 →	+1.587	+1.675	.001	.003	3	19
URINARY_TRACT	ATAD5 →	+1.205	+1.167	<.001	.002	2	20
BONE	XRCC2 →	+1.721	+1.692	.001	.001	3	19
BONE	BLM →	+1.675	+1.713	<.001	.002	3	19
BLOOD_Myeloma	PRC1 →	+1.601	+1.803	<.001	<.001	3	19

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,129 associations by consensus.

FANCI vs NCAPG2 — BLOOD_Myeloma

Explore this scatter interactively →