Across TCGA patient cohorts, FANCG protein abundance is significantly associated with the RNA expression of many other genes, with 338 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible FANCG-associated genes across cancer lineages are EZH2, FAM162A, and TFAP2E. Each is linked with FANCG in more than 1 cancer types. Because this analysis shows association rather than direction, both FANCG-to-partner and partner-to-FANCG results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FANCG→partner) and Y-score (partner→FANCG) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	EZH2 →	+0.965	+0.751	.002	.002	3	1
UCEC	FAM162A →	+0.836	+0.707	.001	<.001	3	1
UCEC	TFAP2E →	+0.751	+0.888	.003	.003	3	1
UCEC	CIT →	+1.081	+0.964	.004	.009	3	1
UCEC	STIL →	+1.201	+0.842	.003	.001	3	1
UCEC	PAICS →	+0.537	+0.666	.005	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 338 associations by consensus.

Exploration

FANCG survival (RNA) · tumor vs normal (RNA) · all FANCG data types