Across TCGA pan-cancer cohorts, FANCF Mutation is linked to patient survival in 3 of 34 cancer types, making it a survival-associated FANCF data layer compared with 23 for mass-spec protein.

The strongest signal is observed in bladder urothelial carcinoma (BLCA), where higher FANCF Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated FANCF expression acts as an unfavorable survival marker.

BLCA, HNSC, and LUSC are the cancer types where FANCF Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
BLCA	OS	Median	All	0.141	0.687	.003	21	view →
HNSC	OS	Median	All	0.191	0.710	.021	6	view →
LUSC	DFS	Median	II,III,IV	0.185	0.709	.018	6	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

Exploration

Same gene, other analysis: FANCF tumor-vs-normal RNA expression · all FANCF data types