Across TCGA patient cohorts, FANCF RNA expression is significantly associated with the protein abundance of many other proteins, with 9,392 significant associations in total. GBM shows the largest number of these associations.

The most reproducible FANCF-associated proteins across cancer lineages are ADNP, C11orf58, and ZKSCAN1. Each is linked with FANCF in more than 4 cancer types. Because this analysis shows association rather than direction, both FANCF-to-partner and partner-to-FANCF results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (FANCF→partner) and Y-score (partner→FANCF) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	ADNP →	+0.316	+0.514	<.001	.001	3	5
BRCA	C11orf58 →	+0.317	+0.445	<.001	<.001	3	5
HNSC	ZKSCAN1 →	+0.407	+0.701	<.001	.002	3	5
HNSC	ARPC5L →	-0.206	-0.429	.004	.005	3	4
COAD	ERCC2 →	+0.192	+0.473	.008	<.001	3	4
HNSC	ALDH1L2 →	-0.541	-0.787	.001	.004	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,392 associations by consensus.

Exploration

FANCF survival (RNA) · tumor vs normal (RNA) · all FANCF data types